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BreathPrint Biomarker

BreathPrint Biomarker

Context:

Recently, the researchers at the S. N. Bose National Centre for Basic Sciences have found the new biomarker called ‘BreathPrint’.

Biomarker:

  • A biomarker is "a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention."
  • Biomarkers are the measures used to perform a clinical assessment such as blood pressure or cholesterol level and are used to monitor and predict health states in individuals or across populations so that appropriate therapeutic intervention can be planned.
  • Biomarkers may be used alone or in combination to assess the health or disease state of an individual.

Details:

  • The new biomarker 'BreathPrint' has been found for the diagnosis of 'Helicobacter pylori' in semi-heavy water (HDO) in human exhaled breath.
  • The biomarker will be used for the early diagnosis of bacteria that causes peptic ulcers.
  • Helicobacter pylori are usually diagnosed by the traditional and invasive painful endoscopy and biopsy tests which are not suitable for early diagnosis and follow-up.
  • The team has already developed a patented ‘Pyro-Breath’ device for the diagnosis of various gastric disorders and Helicobacter pylori infection.

Helicobacter pylori:

  • The term "Helico" means spiral, which indicates that the bacteria are spiral-shaped.
  • It is a common type of bacteria that grows in the digestive tract and has a tendency to attack the stomach lining.
  • H. pylori are adapted to live in the harsh, acidic environment of the stomach. 
  • H. pylori infections are usually harmless, but they’re responsible for the majority of ulcers in the stomach and small intestine.
    • The spiral shape of H. pylori allows them to penetrate the stomach lining, where they’re protected by mucus and the human body’s immune cells are not able to reach them.

Source: PIB