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Cat Que Virus

Cat Que Virus


Scientists from Maximum Containment Laboratory and ICMR-National Institute of Virology have noted the presence of antibodies against the Cat Que virus (CQV) in two human serum samples.

Key findings:

  • The presence of the Cat Que virus has been largely reported in Culex mosquitoes in China and in pigs in Vietnam.
  • For the study, 1020 human serum samples that showed acute febrile illness during 2014-2017 were collected.
  • All these samples were found to be negative for CQV when subjected to the real-time RT-PCR test.
  • However, antibody positivity was recorded in two of the 883 samples that were tested for the presence of antibodies.

Cat Que virus:

  • For CQV, domestic pigs are considered to be the primary mammalian hosts.
  • Antibodies against the virus have been reported in swine reared in China, which indicates that the virus has formed a “natural cycle” in the local area and has the ability to spread in pigs and other animals through mosquitoes.
  • CQV belongs to the Simbu serogroup and infects both humans and economically important livestock species.
  • It was first isolated in 2004 from mosquitoes during the surveillance of arbovirus activity in northern Vietnam.
  • In this study, researchers reported a CQV strain, which was isolated from mosquito samples collected in China in 2006 and 2008

Humans infection:

  • Humans can get infected through mosquitoes as well.
  • In the study, scientists note that because of positivity in human serum samples and the replication capability of CQV in mosquitoes, there is only a “possible disease-causing potential” of CQV in the Indian scenario.
  • Availability of vector, primary mammalian host (swine), and confirmation of CQV from jungle myna signifies the potential of this Orthobunyavirus as a public health pathogen in India.
  • It is not clear that the virus is dangerous or not. Other viruses that belong to the same genus as CQV and are similarly transmitted through mosquitoes include the Cache valley virus that can cause meningitis, the La Crosse virus that can cause pediatric encephalitis.

Source: Indian Express